Mangosteen Overview

Mangosteen is a tropical plant cultivated in areas such as Indonesia, Malaysia, Sri Lanka, Philippines, and Thailand. It has been consumed as a fruit, juice, and in powdered form and used as traditional medicine for generations.  

Mangosteen products typically include the fruit, rind and pulp of the fruit, which contains compounds called xanthones.

Health Benefits of Mangosteen

Proponents claim that mangosteen can also help with the following health problems:

  • Support seasongal allergies
  • Promotes relaxation
  • Supports healthy, normal inflammatory levels
  • Supports the body's innate resistance to pathogens
  • Supports gut health
  • Supports overall cardiovascular function
  • Supports eye health
  • Supports immune system function

Sources of Mangosteen

In North America, fresh mangosteens can be found in Canada and Hawaii but they cannot legally be imported into continental United States due to concerns they transport insects into the country.
Often sold in juice form, mangosteen extract is also available in capsules and powders.

Side Effects of Mangosteen

Research indicates xanthones may interfere with normal blood-clotting. It's not known whether mangosteen xanthones may interact with blood-thinning medication (such as warfarin) and possibly lead to bleeding.

Studies suggest higher doses of xanthones may depress the central nervous system in animals and cause sedation. Xanthones may cause excess sedation when combined with other herbs or medication, and it may be toxic at higher doses. Human studies have not been conducted.



Zhuohong Xie et al. Daily consumption of a mangosteen-based drink improves in vivo antioxidant and anti-inflammatory biomarkers in healthy adults: a randomized, double-blind, placebo-controlled clinical trial. Food Sci Nutr. 2015 Jul; 3(4): 342-348.


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